SMI

About SMI

This author has not yet filled in any details.
So far SMI has created 163 entries.

Lymphoid Aggregates Remodel Lymphatic Collecting Vessels that Serve Mesenteric Lymph Notes in Crohn Disease

Gwendalyn J. Randolph, Shashi Bala, Jean-François Rahier, Michael W. Johnson, Peter L. Wang, ILKe Nalbantoglu, Laurent Dubuquoy, Amélie Chau, Benjamin Pariente, Alex Kartheuser, Bernd H. Zinselmeyer, and Jean-Frederic Colombel

Early pathological descriptions of Crohn disease (CD) argued for a potential defect in lymph transport; however, this concept has not been thoroughly investigated. In mice, poor […]

By |November 23rd, 2016|Categories: Featured Papers, November 2016||0 Comments

Human Norovirus Culture in B Cells

Human norovirus culture in B cells

Melissa K Jones, Katrina R Grau, Veronica Costantini, Abimbola O Kolawole, Miranda de Graaf, Pamela Freiden, Christina L Graves, Marion Koopmans, Shannon M Wallet, Scott A Tibbetts, Stacey Schultz-Cherry, Christiane E Wobus, Jan Vinjé & Stephanie M Karst: Nat Protoc. 2015 Dec; 10(12): 1939-47. Published online 2015 Oct 29. […]

By |November 23rd, 2016|Categories: Protocols, Publications||0 Comments

Vertically Transmitted Fecal IgA Levels Determine Phenotypic Variation

Vertically Transmitted Fecal IgA Levels Determine Extra-Chromosomal Phenotypic Variation

Moon C, Baldridge MT, Wallace MA, Burnham CA, Virgin HW, Stappenbeck TS.

Nature. 2015 Feb 16. doi: 10.1038/nature14139. [Epub ahead of print]

Phenotypic variation between apparently genetically identical mice at different facilities/institutions has been a challenge facing investigators working in many different murine experimental systems. Differences in commensal […]

By |May 1st, 2015|Categories: 2015, 2015 Featured Papers, April 2015, News||0 Comments

Grand Challenges Explorations (GCE) Applications

Grand Challenges Explorations (GCE) has opened application Round 15, and proposals for the six topics listed below are being accepted online through May 13, 2015.

GCE Round 15 topics:
• Addressing Newborn and Infant Gut Health Through Bacteriophage-Mediated Microbiome Engineering
• Explore New Ways to Measure Delivery and Use of Digital Financial Services Data
• Surveillance […]

By |March 23rd, 2015|Categories: 2015, News||0 Comments

Commensal Gram-positive Bacteria Initiate Colitis

Commensal Gram-positive Bacteria Initiates Colitis by Inducing Monocyte/Macrophage Mobilization

Y Nakanishi, T Sato and T Ohteki.

Mucosal Immunology (2015) 8, 152–160; doi:10.1038/mi.2014.53; published online 18 June 2014

The commensal bacteria in the intestine benefit the host immune response. However, breakdown of the intestinal epithelial layer’s barrier function results in the inflow of commensal flora and improper immune […]

Species-specific Expression of Colon T Cell Homing

Role and Species-specific Expression of Colon T Cell Homing Receptor GPR15 in Colitis

Nguyen LP, Pan J, Dinh TT, Hadeiba H, O’Hara E 3rd, Ebtikar A, Hertweck A, Gökmen MR, Lord GM, Jenner RG, Butcher EC, Habtezion A.

Nat Immunol. 2015 Feb;16(2):207-13. doi: 10.1038/ni.3079. Epub 2014 Dec 22.

Recruitment of lymphocytes from circulation is a tissue- and […]

Interleukin (IL)-21 Promotes Intestinal IgA Responses to Microbiota

Interleukin (IL)-21 Promotes Intestinal IgA Responses to Microbiota

Cao AT, Yao S, Gong B, Nurieva RI, Elson CO, Cong Y.

Mucosal Immunol. 2015 Jan 14. doi: 10.1038/mi.2014.134.

The intestinal tract is colonized by trillions of commensal bacteria that live in a mutualistic relationship our bodies. Commensal microbiota-specific Th17 cells are enriched in the intestines and are crucial […]

MyD88 Signaling in T Cells Directs IgA-Mediate Control of Microbiota

MyD88 Signaling in T Cells Directs IgA-Mediated Control of the Microbiota to Promote Health

Jason L. Kubinak, Charisse Petersen, W. Zac Stephens, Ray Soto, Erin Bake, Ryan M. O’Connell, June L. Round.

http://dx.doi.org/10.1016/j.chom.2014.12.009

Alterations to the commensal communities on our bodies can lead to disease, however the mechanisms by which the host can control and sculpt the […]

Lori Rathje Named Executive Director of SMI

Lori Rathje, CAE, has been named Executive Director of the Society for Mucosal Immunology. Lori was previously Association Manager for SMI and served in that position since 2008.

“I am honored to serve as Executive Director of SMI, and to have the opportunity to work with such distinguished leaders to advance their mission,” Rathje said.

Lori […]

By |February 4th, 2015|Categories: 2015, News||0 Comments

JSI 2014 Poster Winner Announced

Congratulations to Dr. Yoshiyuki Goto! He received the Japanese Society for Immunology 2014 poster prize sponsored by Nature Publishing Group and the Society for Mucosal Immunology. The poster prize consists of $200 and 2 year of membership to SMI!

Congratulations Yoshiyuki!

By |February 1st, 2015|Categories: 2015, News||0 Comments