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Commensal Bacteria Protect against Food Allergen Sensitization

Commensal Bacteria Protect against Food Allergen Sensitization

Stefka, AT et al  Commensal bacteria protect against food allergen sensitization.  2014 PNAS USA 111, 13145-13150.

The prevalence of life-threatening anaphylactic responses to food is rising at an alarming rate in many parts of the world. It is increasingly clear that 21st century environmental interventions, including widespread antibiotic use, […]

By |October 10th, 2014|Categories: 2014 Featured Papers, October 2014||0 Comments

SMI’s First President Awarded for Service at UAB

SMI’s first president was Jiri Mestecky, MD, PhD, serving from 1987-1989 has spent the past 45 years at UAB investigating the structure, biosynthesis and function of human and animal immunoglobuilin A (IgA) and immune responses. He also was among the first scientists to develop reliable assays for the measurement of mucosal HIV immune responses, […]

By |October 1st, 2014|Categories: 2014, News||0 Comments

Endoscopic Photoconversion Reveals Trafficking to the Gut

Endoscopic Photoconversion Reveals Unexpectedly Broad Leukocyte Trafficking to and from the Gut

Morton AM, Sefik E, Upadhyay R, Weissleder R, Benoist C, Mathis D.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6696-701. doi: 10.1073/pnas.1405634111. Epub 2014 Apr 21.

Gut-microbiota/immune-cell interactions play important roles in immune system homeostasis and responsiveness, and have been implicated in the […]

Announcing the ICMI 2015 Programming Committee

The ICMI 2015 International Planning Committee is charged with the development of the scientific program including selecting the topics, speakers, and chairs for the scientific sessions and decided on the overall direction of the meeting.

By |September 10th, 2014|Categories: 2014, News||0 Comments

Logo Usage Guidelines

Society for Mucosal Immunology (SMI) Logo Usage Guidelines










By |September 9th, 2014|Categories: Uncategorized||0 Comments

Constant Replenishment from Circulating Monocytes in Adult Mice

Constant Replenishment from Circulating Monocytes Maintains the Macrophage Pool in the Intestine of Adult Mice

Bain CC, Bravo-Blas A, Scott CL, Gomez Perdiguero E, Geissmann F, Henri S, Malissen B, Osborne LC, Artis D, Mowat AM.

Nat Immunol. 2014 Aug 24. doi: 10.1038/ni.2967.

The normal intestine contains large numbers of macrophages that play crucial roles in homeostasis, […]

Transcription Factor T Bet Regulates Lymphocyte Maturation

Transcription Factor T-bet Regulates Intraepithelial Lymphocyte Functional Maturation

Reis BS, Hoytema van Konijnenburg DP, Grivennikov SI, Mucida D.

Immunity. 2014 Aug 21;41(2):244-56. doi: 10.1016/j.immuni.2014.06.017.

IELs police the single-cell layer of intestinal epithelium, a fine boundary that spans as much as 400 square meters and allows nutrients in and wastes out. Nearly all IELs belong to a group […]

Transcription Factor T Bet is Induced by IL-15

The Transcription Factor T Bet Is Induced by IL-15 and Thymic Agonist Selection and Controls CD8αα(+) Intraepithelial Lymphocyte Development

Klose CS, Blatz K, d’Hargues Y, Hernandez PP, Kofoed-Nielsen M, Ripka JF, Ebert K, Arnold SJ, Diefenbach A, Palmer E, Tanriver Y.

Immunity. 2014 Aug 21;41(2):230-43. doi: 10.1016/j.immuni.2014.06.018.

CD8αα(+) intraepithelial lymphocytes (IELs) are instrumental in maintaining the epithelial […]

Epigenetic Regulator UHRF1 Facilitates Proliferation of T Cells

The Epigenetic Regulator UHRF1 Facilitates the Proliferation and Maturation of Colonic Regulatory T Cells

Obata Y, Furusawa Y, Endo TA, Sharif J, Takahashi D, Atarashi K, Nakayama M, Onawa S, Fujimura Y, Takahashi M, Ikawa T, Otsubo T, Kawamura YI, Dohi T, Tajima S, Masumoto H, Ohara O, Honda K, Hori S, Ohno H, Koseki […]

Intraepithelial T Cells Drive into Unusual MHC Reactivities

αβT Cell Receptors Expressed by CD4(-)CD8αβ(-) Intraepithelial T Cells Drive Their Fate into a Unique Lineage with Unusual MHC Reactivities

Mayans S, Stepniak D, Palida SF, Larange A, Dreux J, Arlian BM, Shinnakasu R, Kronenberg M, Cheroutre H, Lambolez F.

Immunity. 2014 Aug 21;41(2):207-18. doi: 10.1016/j.immuni.2014.07.010. Epub 2014 Aug 14.

The development pathway and major histocompatibility complex […]