About SMI

This author has not yet filled in any details.
So far SMI has created 163 entries.

The Unprecedented Ebola Outbreak of 2014

The Ebola virus disease outbreak of 2014 centered in West Africa is the most extensive outbreak yet of this viral hemorrhagic fever with a high mortality rate (60-90% in most previous outbreaks). On August 8, the WHO declared the 2014 outbreak to be a Public Health Emergency of International Concern.

The unprecedented 2014 Ebola outbreak […]

By |September 1st, 2014|Categories: 2014, News||0 Comments

Attention Young Investigators: ICMI 2015 Award Opportunities

SMI is proud to support young scientists in the field of mucosal immunology and will provide up to 40 travel awards for the upcoming ICMI congress. Travel awards will range from $500-$1,000 and will be given to young investigators who submit the highest scoring abstracts. Eligible travel award participants must be under the age […]

By |September 1st, 2014|Categories: 2014, News||0 Comments

Unique Lamina Propria Stromal Cells

Unique Lamina Propria Stromal Cells Imprint the Functional Phenotype of Mucosal Dendritic Cells

Vicente-Suarez I, Larange A, Reardon C, Matho M, Feau S, Chodaczek G, Park Y, Obata Y, Gold R, Wang-Zhu Y, Lena C, Zajonc DM, Schoenberger SP, Kronenberg M, Cheroutre H.

Mucosal Immunol. 2014 Jun 18. doi: 10.1038/mi.2014.51

The featured article provides supporting evidence  that […]

Elevated T Cell Receptor Signaling Identifies a Thymic Precursor

Elevated T Cell Receptor Signaling Identifies a Thymic Precursor to the TCRαβ(+)CD4(-)CD8β(-) Intraepithelial Lymphocyte Lineage

McDonald BD, Bunker JJ, Ishizuka IE, Jabri B, Bendelac A.

Immunity. 2014 Aug 21;41(2):219-29. doi: 10.1016/j.immuni.2014.07.008. Epub 2014 Aug 14.

The developmental pathway that TCRαβ+CD8αα+ intestinal intraepithelial lymphocytes (here called unconventional iIEL) follow has long remained a mystery. In their recent paper, […]

By |August 25th, 2014|Categories: August 2014, Featured Papers||0 Comments

The Reichstag Awaits You at ICMI 2015

While attending the International Congress for Mucosal Immunology in July 2015, be sure to take time to see some of the historic landmarks in Berlin, Germany.

The Reichstag Building is a historical edifice in Berlin, Germany constructed to the Imperial Diet of the German Empire. It was opened in 1894 and housed the Diet until […]

By |August 4th, 2014|Categories: 2014, News||0 Comments

Educate with Principles of Mucosal Immunology

Principles of Mucosal Immunology, the official textbook of the Society for Mucosal Immunology, examines the commonalities of the mucosal immune system. It focuses on all compartments, but especially those for which the largest body of information is available, such as the small and large intestine, lung and upper airways, genital and urinary systems, and […]

By |August 4th, 2014|Categories: 2014, News||0 Comments

Compression-Based Distance (CBD): Microbiota Composition

Fang, Y., Chia, N., White, B., Schook, L. “Compression-based Distance (CBD): A Simple, Rapid, and Accurate Method for Microbiota Composition Comparison.” BMC Bioinformatics. BMC Bioinformatics, 23 Apr. 2013.

Perturbations in intestinal microbiota composition have been associated with a variety of gastrointestinal tract-related diseases. The alleviation of symptoms has been achieved using treatments that alter the gastrointestinal tract […]

By |July 25th, 2014|Categories: Gastrointestinal System, Protocols||0 Comments

Incubation of Precision-Cut Liver and Intestinal Slices

Preparation and Incubation of Precision-cut Liver and Intestinal Slices for Application in Drug Metabolism. de Graaf IA, Olinga P, de Jager MH, Merema MT, de Kanter R, van de Kerkhof EG, Groothuis GM.  Nat Protoc. 2010 Sep;5(9):1540-51. doi: 10.1038/nprot.2010.111. Epub 2010 Aug 19.

Precision-cut tissue slices (PCTS) are viable ex vivo explants of tissue with a […]

By |July 24th, 2014|Categories: Gastrointestinal System, Protocols||0 Comments

Methods for Generating and Colonizing Gnotobiotic Zebrafish

Pham LN, Kanther M, Semova I, Rawls JF.  Nat Protoc. 2008;3(12):1862-75. doi: 10.1038/nprot.2008.186.

Vertebrates are colonized at birth by complex and dynamic communities of microorganisms that can contribute significantly to host health and disease. The ability to raise animals in the absence of microorganisms has been a powerful tool for elucidating the relationships between animal […]

By |July 24th, 2014|Categories: Gastrointestinal System, Protocols||0 Comments

Chemically Induced Mouse Models of Intestinal Inflammation

Wirtz S, Neufert C, Weigmann B, Neurath MF.  Nat Protoc. 2007;2(3):541-6.

Animal models of intestinal inflammation are indispensable for our understanding of the pathogenesis of Crohn’s disease and ulcerative colitis, the two major forms of inflammatory bowel disease in humans. Here, we provide protocols for establishing murine 2,4,6-trinitro benzene sulfonic acid (TNBS)-, oxazolone- and both […]

By |July 24th, 2014|Categories: Gastrointestinal System, Protocols||0 Comments