Differential Role of Dendritic Cells and Lymphoid Cells

Segmented Filamentous Bacteria Antigens Presented by Intestinal Dendritic Cells Drive Mucosal Th17 Cell Differentiation

Yoshiyuki Goto, Casandra Panea, Gaku Nakato, Anna Cebula, Carolyn Lee, Marta Galan Diez, Terri M. Laufer, Leszek Ignatowicz, and Ivaylo I. Ivanov.

Immunity. 2014 Apr 17;40(4):594-607. doi: 10.1016/j.immuni.2014.03.005. Epub 2014 Mar 27.

How commensal bacteria modulate mucosal T cell responses remains poorly understood. […]

By |June 13th, 2014|Categories: 2014 Featured Papers, April 2014||0 Comments

A Shigella Effector Dampens Inflammation

A Shigella Effector Dampens Inflammation by Regulating Epithelial Release of Danger Signal ATP Through Production of the Lipid Mediator PtdIns5P

Puhar A, Tronchère H, Payrastre B, Nhieu GT, Sansonetti PJ.

Immunity. 2013 Dec 12;39(6):1121-31. doi: 10.1016/j.immuni.2013.11.013.

This study showed that in intestinal epithelial cells enteric pathogens Shigella, Salmonella and enteropathogenic Escherichia coli (EPEC) induce rapid, regulated release […]