Epigenetic Regulator UHRF1 Facilitates Proliferation of T Cells

The Epigenetic Regulator UHRF1 Facilitates the Proliferation and Maturation of Colonic Regulatory T Cells

Obata Y, Furusawa Y, Endo TA, Sharif J, Takahashi D, Atarashi K, Nakayama M, Onawa S, Fujimura Y, Takahashi M, Ikawa T, Otsubo T, Kawamura YI, Dohi T, Tajima S, Masumoto H, Ohara O, Honda K, Hori S, Ohno H, Koseki […]

Intraepithelial T Cells Drive into Unusual MHC Reactivities

αβT Cell Receptors Expressed by CD4(-)CD8αβ(-) Intraepithelial T Cells Drive Their Fate into a Unique Lineage with Unusual MHC Reactivities

Mayans S, Stepniak D, Palida SF, Larange A, Dreux J, Arlian BM, Shinnakasu R, Kronenberg M, Cheroutre H, Lambolez F.

Immunity. 2014 Aug 21;41(2):207-18. doi: 10.1016/j.immuni.2014.07.010. Epub 2014 Aug 14.

The development pathway and major histocompatibility complex […]

Unique Lamina Propria Stromal Cells

Unique Lamina Propria Stromal Cells Imprint the Functional Phenotype of Mucosal Dendritic Cells

Vicente-Suarez I, Larange A, Reardon C, Matho M, Feau S, Chodaczek G, Park Y, Obata Y, Gold R, Wang-Zhu Y, Lena C, Zajonc DM, Schoenberger SP, Kronenberg M, Cheroutre H.

Mucosal Immunol. 2014 Jun 18. doi: 10.1038/mi.2014.51

The featured article provides supporting evidence  that […]

Elevated T Cell Receptor Signaling Identifies a Thymic Precursor

Elevated T Cell Receptor Signaling Identifies a Thymic Precursor to the TCRαβ(+)CD4(-)CD8β(-) Intraepithelial Lymphocyte Lineage

McDonald BD, Bunker JJ, Ishizuka IE, Jabri B, Bendelac A.

Immunity. 2014 Aug 21;41(2):219-29. doi: 10.1016/j.immuni.2014.07.008. Epub 2014 Aug 14.

The developmental pathway that TCRαβ+CD8αα+ intestinal intraepithelial lymphocytes (here called unconventional iIEL) follow has long remained a mystery. In their recent paper, […]

By |August 25th, 2014|Categories: August 2014, Featured Papers||0 Comments