Mouse Model of Oropharyngeal Candidiasis

Solis NV, Filler SG.  Nat Protoc. 2012 Mar 8;7(4):637-42. doi: 10.1038/nprot.2012.011.

Oropharyngeal candidiasis is a frequent cause of morbidity in patients with defects in cell-mediated immunity or saliva production. Animal models of this infection are important for studying disease pathogenesis and evaluating vaccines and antifungal therapies. Here we describe a simple mouse model of oropharyngeal […]

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Examining the Role of NALT in Mouse Responses to Vaccines

Cisney, E. D., Fernandez, S., Hall, S. I., Krietz, G. A., Ulrich, R. G.  J. Vis. Exp. (66), e3960, doi:10.3791/3960 (2012).

The nasopharyngeal-associated lymphoreticular tissues (NALT) found in humans, rodents, and other mammals, contribute to immunity in the nasal sinuses(1-3). The NALT are two parallel bell-shaped structures located in the nasal passages above the hard […]

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