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Postdoctoral Fellow (Immunology) - University of Toronto

Posted On

September 2, 2022

Job Posting Expiration Date

September 30, 2022

Position Title

Postdoctoral Fellow (Immunology)

Organization

University of Toronto

Location (City & Country)

Toronto, Canada

Category

University

Position Type

Full Time

Education & Experience Requirements

PhD

Salary Range

50-65K CAD

How to Apply

All individuals interested in this position must submit CV, a Cover letter, and references contact information to ken.croitoru@sinaihealth.ca and wturpin@lunenfeld.ca or apply directly to sciencecareers.org website by the closing date. Application submitted before the closing date will be consider. The position will remain open until filled.

Organization Description

N/A

Position Description

Area of Research: We are looking for a highly motivated scientist with a track record of creativity in developing experimental strategies and a knowledge base in any or all of the following: mucosal immunology; T cell biology; animal models; microbiome analysis and microbiota culture.


Description of duties: Under the guidance of Dr. Croitoru the candidate is expected to draft and present research plans and projects, carry out individual experiments, analyze and present data, prepare manuscripts for publication and present data at national and international meetings. The Postdoctoral Research Fellow will be assessing how pre disease microbiota promote or induce inflammation when transfer into gnotobiotic colitis mouse models. In addition, the pre disease microbiota will be characterized for its functional properties in vivo including mucolytic, proteolytic, glycosidasic, bile acid degradation capacity. The candidate will also test for the immunoreactivity of pre disease microbiota. We are looking for a highly motivated scientist with a track record of creativity in developing experimental strategies and a knowledge base in the following: mucosal immunology; T cell biology; animal models; and/or microbiology. A PhD in Immunology, Molecular Biology, Microbiology, Cell Biology or a related field, is required. The fellow will have the opportunity to work with established investigators in a large international study with access to a very large biosample repository as part of the GEM project (http://www.gemproject.ca/). The candidate will be responsible to work with unique samples collected before the onset of the disease.

Required qualifications: A PhD in Immunology, Molecular biology, Biotechnology, Life sciences, Pathology, Cellular Biology, and/or Microbiology is required.
• Experience in mouse handling, tissue culture, immunohistochemistry, microscopy and molecular biology
• Experience in gnotobiology, and microbial transplant
• Must be a team player, versatile, flexible, and self-motivated with strong communication/organizational skills and attention to detail
• Molecular biology technique (PCR, qPCR, Elisa)
• Evidence of scientific accomplishment via peer-reviewed publications
• Mastery of spoken and written scientific English
• skills and attention to detail
• Imaging methods (confocal laser scanning microscopy) would be an asset
• Mouse model of colitis would be an asset
• Microbiology technique (culturing, strain isolation, anaerobic chamber)
• Experience with fastidious microbes
• Bioinformatic (16S sequencing, transcriptomic)
• Flow cytometry would be an asset
• Organization skills to handle a large collection of bacterial strains
• Familiar with IgA/IgG seq would be an asset
• Experience with invitro bacterial assay (Gram coloration, Analytical profile index (API system), amido black assay etc.)